The news comes as a key boost to Arsene Wenger as he looks to haul down league leaders Chelsea.

Mustafi, a £34million arrival from Valencia in the summer, has formed a formidable central-defensive partnership with Laurent Koscielny this season.

Arsenal have not lost a game Mustafi has featured in so far this season. Similarly, they have lost two of the three Premier League games he has missed owing to the hamstring injury.

Danny Welbeck, who has missed eight months with a knee injury, could also be considered for a first-team return after stepping up his training plan this week.

Alex Oxlade-Chamberlain (hamstring), Theo Walcott (calf) and Kieran Gibbs (knee) are set to miss the visit of Palace.

Meanwhile, right-back Mathieu Debuchy has spoken about the deterioration of his relationship with Wenger.

Debuchy arrived from Newcastle in 2014 but has lost his place to the excellent Hector Bellerin.

The Frenchman, who has played once for the club this season, has been on the peripheries of the Arsenal squad ever since and was loaned out to Bordeaux last January.

And Debuchy said: ‘We acknowledge each other, we say hello, nothing more.

‘I had opportunities at the end of the transfer window. Unfortunately, the club didn’t want to let me go.

‘I had a good pre-season, I gave my all, but from the first game, I wasn’t in the squad. It was a real blow. I said to myself that things weren’t starting well.’

Similarly, Arsenal rebuffed a loan approach from rivals Manchester United last January, which didn’t go down too well with Debuchy.

‘I wasn’t playing a lot, it was United, there’s nothing else to say,’ he added. ‘For me, it was almost unexpected, but the coach said no.

‘It’s something I did not appreciate. He wasn’t using me, so I didn’t see his interest in doing that.’

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